-------------------- Hypothyroidism: -------------------- Definition: is a condition in which your thyroid gland doesn't produce enough of certain crucial hormones. How does Hypothyroidism affect the metabolism of the human body? It slows down the rate of metabolism enormously. How exactly does it slow down the rate? <This will be shown through diagrams>
Explanation: In this diagram we can see that hypothyroidism has many side effects and one of them is weight gain, fatigue and loss of appetite. Weight gain causes fatigue which makes it harder for a person to walk around and exercise to keep a healthy balance. It also causes a loss in appetite which contributes to the inability to maintain a healthy eating balance. All these factors cause the metabolism rate in a human body to decrease and this decrease will not allow for a good break down of fats in the body.
Graph of Thyroid-hormone production rate vs metabolic rate
Explanation: Metabolic rate depends on the amount of thyroid-hormones produced. As we can see in this graph hypothyroidism reduces the rate of thyroid-hormones produced it is at about less than 50g/day which is less than 50% of the normal it also in turn causes the metabolism rate to decrease as well it at about -25% less than normal. This graphs shows just how badly hypothyroidism affects the metabolic rate in the human body.
Table of physiological effects hypothyroidism on metabolic rate/metabolism
Explanation: In this table we can see how low levels of thyroid-hormone production (hypothyroidism) can decrease all types of metabolism. For example we can see by the arrow pointing downwards in the metabolic rate that it has decreased. It has also decreased the gluconeogenesis and glycogenesis in carbohydrate metabolism. It is known that “ Thyroid hormones enhance the availability of the starting materials required for increased gluconeogenic activity (i.e., amino acids and glycerol), and they specifically induce the expression of several key gluconeogenic enzymes, including phosphoenolpyruvate carboxykinase, pyruvate carboxylase, and glucose 6-phosphatase.” But when there’s a decrease in them it will lower the rate of metabolism.